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The BIL&GIN database is designed for investigating the cognitive, behavioral, genetic, and brain morphological/functional correlates of hemispheric specialization.

The database contains records from a sample of 453 adult participants enriched in left-handers (45%, N=205) as compared to the general population. For each subject, socio-demographic data, hand and eye laterality, family handedness, and cognitive abilities in the language, motor, visuo-spatial, and numerical domains have been recorded. T1-MRI and DTI data were also acquired, as well as resting-state functional MRI.

Taskevoked functional MRI was performed in a sub-sample of 303 subjects (157 left-handers) using a customized functional battery of 16 cognitive tasks exploring the same three cognitive domains. Performances at the tasks executed in the magnet as well as postacquisition debriefing were recorded. A saliva sample was obtained from the subjects of this sub-sample from which DNA was extracted.

The BIL&GIN contains results of imaging data processing for each subject, namely maps of tissue (GM, WM, CSF) probability, cortical thickness, cortical surface, and diffusion parameters as well as regional values of these phenotypes for regions of both AAL and FreeSurfer parcellations. For the subjects who underwent FMRI, individual SPM contrast maps for each of the 8 runs were also calculated and included in the database, as well as corresponding BOLD variations in ROIs of the AAL and AICHA atlases, and Wilke’s hemispheric functional lateralization index.

The BIL&GIN data sharing is based on a collaborative model.

Request for joint research projects involving use or transfer of data from the BIL&GIN can be made through this form.

Description of the BIL&GIN database:

(1) Basic characteristics of the BIL&GIN participants according to self-reported handedness. Note that 2 participants had no eye sighting dominance. FTT: finger tapping test. LH: left-handers; RH: right-handers.

(2) CogBATHS. Battery of cognitive tests performed by the participants of the BIL&GIN and mean results in the population.

(3) MRI sequences used for the FunBATHS.

(4) FunBATHS.
Description of the functional battery of tasks performed by the subjects during the two FMRI sessions.

(5) Parameters for each run of the FUNBATHS.
All runs but the #5 had an event-related design. Session order and run order within a session were randomized. For the description of reference blocks condition, see Table 3. FT: finger tapping; VGS: visually guided saccades; LBJ: line bisection judgement.

(6) Description of the number of run exclusion for the FunBatHS.

(7) Available cerebral phenotypes for the FunBatHS.

(8) Contact for database access through this form.