MICCA is a Matlab toolbox which implement a multi-scale unsupervised clustering algorithm of independent components detected using single subject independent component analysis (ICA) from a subject cohort. ICA is a powerful way to investigate functional connectivity of the human brain recorded by functional magnetic resonance imaging (fMRI).
Original reference
A novel group ICA approach based on multi-scale individual component clustering. Application to a large sample of fMRI data, Mikaël Naveau, Gaëlle Doucet, Nicolas Delcroix, Laurent Petit, Laure Zago, Fabrice Crivello, Gaël Jobard, Emmanuel Mellet, Nathalie Tzourio-Mazoyer, Bernard Mazoyer, Marc Joliot, Neuroinformatics (2012) 10:269-285
https://dx.doi.org/10.1007/s12021-012-9145-2
Application
Here, we provide some illustrations of the results of the article published in Neuroinformatics :
- Atlas of the resting state networks detected with MICCA : Mango applet
- Multilevel model order analysis
We compared MICCA and Concat-ICA [Calhoun, V.D., Adali, T., Pearlson, G.D., Pekar, J.J., 2001. A method for making group inferences from functional MRI data using independent component analysis. Human Brain Mapping 14, 140–151.] results using different model order (number of estimated components). We used a hierarchical representation of this multilevel model order analysis to investigate stability of both MICCA and Concat-ICA. We provide a pdf version of results and a Tulip file which allow a dynamical visualization of the hierarchical representation [Tulip is an information visualization framework dedicated to the analysis and visualization of relational data. You can download Tulip here.].