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ZAGO Laure

Title: Ph.D.

Status: Researcher (CNRS)

CONTACTS:
Address: University of Bordeaux, PAC Carreire, 146 rue Léo-Saignat, Case 71, CS 61292, 33076 Bordeaux FRANCE
Phone: +33 547 304 396
Email: laure.zago@u-bordeaux.fr

Degrees:

  • 2000 : Ph.D. in Neuropsychology (University of Lyon 1)
  • 1997 : DEA in Neuropsychology (University of Lyon 1)
  • 1996 : DEA in Cognitive Sciences (EHESS, Universities of Paris 6, Toulouse 3, Polytechnic School)
  • 1995 : Master in Experimental Psychology (University of Aix-Marseille)

Career:

I obtained my Ph.D. in Neuropsychology from the University of Lyon 1 and worked as a post-doctoral fellow at the Steve Kosslyn’s lab (Department of Psychology, Harvard University, Cambridge, USA), and Moshe’s Bar lab (Martinos Center for Biomedical Imaging, Mass Gen. Hospital, Harvard Medical School, Boston, USA), before being recruited by the CNRS in the Neurofunctional Imaging Group (Dr B. Mazoyer). By combining multimodal neuroimaging approach and behavioural measures, I study the cerebral bases of calculation and number processing, and the relationships with the hemispheric specialization (HS) of language and spatial attention. HS, also referred to as hemispherical dominance, is a remarkable trait in the organization of the human brain. It relates to the observation that a lesion of a cerebral hemisphere results in a loss of a specific cognitive function. For around 80% of subjects, language is a function of the left hemisphere (LH). With the remaining 20%, variability in hemispheric organization is such that the right hemisphere (RH) can play the dominant role for language. The RH is dominant for visuo-spatial functions, but little is known about the variability

Current Research topics:

My current research focuses on the identification of factors and biomarkers that play a role in establishing the anatomical (MRI, DTI) and functional (fMRI) bases of calculation and number processing, and their association with the HS of language and spatial attention in healthy subjects. To assess these issues, I work on multimodal neuroimaging and behavioral databases including large cohorts of individuals.

Expertise in:

Functional and anatomical neuroimaging of numerical and attentional cognitive functions

Hemispheric specialization of spatial attention

Publications (since 2007):

  • 1. Zago L; Petit L; Turbelin MR; et al. (2008) How verbal and spatial manipulation networks contribute to calculation: An fmri study. Neuropsychologia Volume: 46 Issue: 9 Pages: 2403-2414 (PDF)
  • 2. Leroux G; Spiess J; Zago L; et al. (2009) Adult brains don’t fully overcome biases that lead to incorrect performance during cognitive development: an fmri study in young adults completing a Piaget-like task. Developmental Science Volume: 12 Issue: 2 Pages: 326-338.(PDF)
  • 3. Petit L; Zago L; Vigneau M; et al. (2009) Functional Asymmetries Revealed in Visually Guided Saccades: An fmri Study. Journal Of Neurophysiology Volume: 102 Issue: 5 Pages: 2994-3003. (PDF)
  • 4. Delamillieure P; Doucet G; Mazoyer B; Turbelin M.R; Delcroix N; Mellet E; Zago L; Crivello F; Petit L; Tzourio-Mazoyer N; Joliot M (2010) The resting state questionnaire: An introspective questionnaire for evaluation of inner experience during the conscious resting state. Brain Research Bulletin Volume: 81 Issue: 6 Pages: 565-573. (PDF)
  • 5. Tzourio-Mazoyer N; Simon G; Crivello F; Jobard G; Zago L; et al. (2010) Effect of Familial Sinistrality on Planum Temporale Surface and Brain Tissue Asymmetries. Cerebral Cortex Volume: 20 Issue: 6 Pages: 1476-1485. (PDF)
  • 6. Tzourio-Mazoyer N, Petit L, Razafimandimby A, Crivello F, Zago L, Jobard G, Joliot M, Mellet E, Mazoyer B (2010). Left hemisphere lateralization for language in right-handers is controlled in part by familial sinistrality, manual preference strength, and head size. J Neuroscience 30, 40, 13314-13318. (PDF)
  • 7. Courtin C; Herve P.Y; Petit L; Zago L; Vigneau M; et al. (2010) The neural correlates of highly iconic structures and topographic discourse in French Sign Language as observed in six hearing native signers. Brain And Language Volume: 114 Issue: 3 Pages: 180-192. (PDF)
  • 8. Mellet E; Laou L; Petit L; Zago L; Mazoyer B; Tzourio-Mazoyer N. (2010) Impact of the Virtual Reality on the Neural Representation of an Environment. Human Brain Mapping Volume: 31 Issue: 7 Pages: 1065-1075. (PDF)
  • 9. Zago L; Petit L; Mellet E; Joliot M; Mazoyer B; Tzourio-Mazoyer N. (2010) Neural correlates of counting large numerosity. ZDM Mathematics Education Volume: 42 Issue: 6 Pages: 569-577. (PDF)
  • 10. Beaucousin V, Zago L, Herve P-Y, Strelnikov K, Crivello F, Mazoyer B, Tzourio-Mazoyer N (2011) Sex-dependent modulation of activity in the neural networks engaged during emotional speech comprehension. Brain Research Volume: 1390 Pages: 108-117. (PDF)
  • 11. Doucet G, Naveau M, Petit L, Delcroix N, Zago L, Crivello F, Jobard G, Tzourio-Mazeoyer N, Mazoyer B, Mellet E And Joliot M (2011) Brain activity at rest : a multiscale hierarchical functional organization. Journal of Neurophysiology Volume: 105 Issue: 6 Pages: 2753-2763. (PDF)
  • 12. Vigneau M, Beaucousin V, Herve P-Y, Jobard G, Petit L, Crivello F, Mellet E, Zago L, Mazoyer B, Tzourio-Mazoyer N (2011) What is right-hemisphere contribution to honological, lexico-semantic and sentence processing ? Insights from a meta-analysis. NeuroImage Volume: 54 Issue: 1 Pages: 577-593. (PDF)
  • 13. Courtin C, Jobard G, Vigneau M, Beaucousin V, Razafimbandimby A, Herve P-Y, Mellet E, Zago L, Petit L, Mazoyer B, Tzourio-Mazoyer N (2011) A common neural system is activated in hearing non-signers to process French Sign Language and spoken French. Brain Research Bulletin Volume: 84 Issue: 1 Pages: 75-87. (PDF)
  • 14. Naveau M, Doucet G, Delcroix N, Petit L, Zago L, Crivello F, Jobard G, Mellet E, Tzourio-Mazoyer N, Mazoyer B, Joliot M (2012) A novel group ICA approach based on multiscale individual component clustering. Application to a large sample of fMRI data. Neuroinformatics Volume: 10 Issue: 3 Pages: 269-285. (PDF)
  • 15. Doucet G, Naveau M, Petit L, Zago L, Crivello F, Jobard G, Delcroix N, Mellet E, Tzourio-Mazoyer N, Mazoyer B, Joliot M (2012) Patterns of hemodynamic low-frequency oscillations in the brain are modulated by the nature of free thought during rest. NeuroImage Volume: 59 Issue: 4 Pages: 3194-3200. (PDF)
  • 16. Tzourio-Mazoyer N and Zago L (2012). Is there a neural dissociation between language and reasoning? Trends in Cognitive Neurosciences Volume: 16 Issue: 10 Pages: 494-495 (PDF)